Berberine HCl

Berberine HCl

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Berberine HCl

Berberine HCl

Rated 4.7 out of 5 stars
122 Reviews
Regular price $39.95
Regular price Sale price $39.95
Unit price $39.95
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Supports Metabolic Health.*
Supports Healthy Glucose & Lipid Levels.*
Supports Healthy Weight Management.*

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97% Pure Berberine HCL from Berberis Aristata Root Extract.
Plant Derived Alkaloid for Metabolic Support.*
Branded Raw Material Sourced from Quality Supplier (Rebersa®).
Easy-to-swallow Capsules suitable for Vegetarians.
Gluten Free, Soy Free, Dairy Free, and Third-Party Tested.
Formulated according to current Good Manufacturing Practices (cGMP).
Formulated, Tested, and Packed in the USA.

Suggested Usage

Take one capsule daily with food or as recommended by your health care professional.


Berberine HCl
(Berberis Aristata Extract) (Root) (Rebersa®)
Other Ingredients: Vegetable Cellulose Capsules, Silicon Dioxide, MCT Powder.

  • Gluten Free

  • Soy Free

  • Dairy Free

  • Vegetarian

  • GMP Certified Facility

  • third-party-tested-logo

    Third Party Tested


Why Sandhu’s Berberine? ​

Optimal metabolism is essential for maintaining long-term health and wellness. An unhealthy diet, poor hygiene, and inactive lifestyle, and aging may impact the natural metabolism. Berberine, a natural potent compound found in several plants, including barberry, has been traditionally used in Chinese and Ayurvedic medicine as a wellness aid. Also, Recent scientific studies have shown that berberine may support healthy metabolism, immune function, etc.*(1-14)Adding such multi-beneficial berberine in your routine is easy with Sandhu’s berberine supplement that offers 97% pure berberine HCL.*(1-4)​


How Does it Works?​

Berberine supports metabolic enzymes and helps to keep you active through a healthy metabolism.*(1,3,8)Also, by helping the uptake of glucose from the circulation into cells, it supports glycolysis and helps maintain healthy glucose levels which are already in the normal range.*(3-5,10)Additionally, this plant-derived alkaloid supports lipid/ fatty acid metabolism to maintain healthy energy levels.*(4-9)Berberine helps in healthy weight management by supporting glucose and lipid metabolism.*(8-11)Furthermore, it also helps balance the healthy level of gut-friendly bacteria and supports healthy gastrointestinal function.*(10,14)​

  1. Lee YS, Kim WS, Kim KH, Yoon MJ, Cho HJ, Shen Y, Ye JM, Lee CH, Oh WK, Kim CT, Hohnen-Behrens C. Berberine, a natural plant product, activates AMP-activated protein kinase with beneficial metabolic effects in diabetic and insulin-resistant states. Diabetes. 2006 Aug 1;55(8):2256-64.​
  2. An Y, Sun Z, Zhang Y, Liu B, Guan Y, Lu M. The use of berberine for women with polycystic ovary syndrome undergoing IVF treatment. Clinical endocrinology. 2014 Mar;80(3):425-31.​
  3. Pérez-Rubio KG, González-Ortiz M, Martínez-Abundis E, Robles-Cervantes JA, Espinel-Bermúdez MC. Effect of berberine administration on metabolic syndrome, insulin sensitivity, and insulin secretion. Metabolic syndrome and related disorders. 2013 Oct 1;11(5):366-9.​
  4. Yin J, Xing H, Ye J. Efficacy of berberine in patients with type 2 diabetes mellitus. Metabolism. 2008 May 1;57(5):712-7.​
  5. Gu Y, Zhang Y, Shi X, Li X, Hong J, Chen J, Gu W, Lu X, Xu G, Ning G. Effect of traditional Chinese medicine berberine on type 2 diabetes based on comprehensive metabonomics. Talanta. 2010 May 15;81(3):766-72.​
  6. Derosa G, D'Angelo A, Bonaventura A, Bianchi L, Romano D, Maffioli P. Effects of berberine on lipid profile in subjects with low cardiovascular risk. Expert opinion on biological therapy. 2013 Apr 1;13(4):475-82.​
  7. Zhao JV, Yeung WF, Chan YH, Vackova D, Leung JY, Ip DK, Zhao J, Ho WK, Tse HF, Schooling CM. Effect of berberine on cardiovascular disease risk factors: a mechanistic randomized controlled trial. Nutrients. 2021 Jul 26;13(8):2550.​
  8. Wei W, Zhao H, Wang A, Sui M, Liang K, Deng H, Ma Y, Zhang Y, Zhang H, Guan Y. A clinical study on the short-term effect of berberine in comparison to metformin on the metabolic characteristics of women with polycystic ovary syndrome. European journal of endocrinology. 2012 Jan;166(1):99-105​
  9. Hu Y, Ehli EA, Kittelsrud J, Ronan PJ, Munger K, Downey T, Bohlen K, Callahan L, Munson V, Jahnke M, Marshall LL. Lipid-lowering effect of berberine in human subjects and rats. Phytomedicine. 2012 Jul 15;19(10):861-7.​
  10. Zhang X, Zhao Y, Zhang M, Pang X, Xu J, Kang C, Li M, Zhang C, Zhang Z, Zhang Y, Li X. Structural changes of gut microbiota during berberine-mediated prevention of obesity and insulin resistance in high-fat diet-fed rats.​
  11. Ilyas Z, Perna S, Al-Thawadi S, Alalwan TA, Riva A, Petrangolini G, Gasparri C, Infantino V, Peroni G, Rondanelli M. The effect of Berberine on weight loss in order to prevent obesity: A systematic review. Biomedicine & Pharmacotherapy. 2020 Jul 1;127:110137.​
  12. Cheng F, Wang Y, Li J, Su C, Wu F, Xia WH, Yang Z, Yu BB, Qiu YX, Tao J. Berberine improves endothelial function by reducing endothelial microparticles-mediated oxidative stress in humans. International journal of cardiology. 2013 Aug 10;167(3):936-42.​
  13. Ma YG, Liang L, Zhang YB, Wang BF, Bai YG, Dai ZJ, Xie MJ, Wang ZW. Berberine reduced blood pressure and improved vasodilation in diabetic rats. Journal of molecular endocrinology. 2017 Oct 1;59(3):191-204.​
  14. Ming J, Yu X, Xu X, Wang L, Ding C, Wang Z, Xie X, Li S, Yang W, Luo S, He Q. Effectiveness and safety of Bifidobacterium and berberine in human hyperglycemia and their regulatory effect on the gut microbiota: a multi-center, double-blind, randomized, parallel-controlled study. Genome Medicine. 2021 Dec;13(1):1-4.​
  15. Shirwaikar A, Shirwaikar A, Rajendran K, Punitha IS. In vitro antioxidant studies on the benzyl tetra isoquinoline alkaloid berberine. Biological and Pharmaceutical Bulletin. 2006;29(9):1906-10.​

Frequently Asked Questions

Is berberine safe to take?

When taken at the appropriate dose, berberine is generally considered safe for most individuals. However, it is important to consult with a healthcare professional, especially if you have any underlying health conditions or taking other medications.

Can berberine interact with medications?

Berberine has the potential to interact with certain medications, particularly those metabolized by the liver.* It may also interact with drugs that lower blood sugar or blood pressure.* Consult with a healthcare professional to ensure there are no potential interactions with your current medications.

What is the recommended dosage of berberine?

The optimal dosage of berberine may vary depending on the individual and the specific health condition. It is best to follow the dosage instructions provided on the supplement or consult with a healthcare professional for personalized guidance.

Are there any side effects associated with berberine supplementation?

Some individuals may experience gastrointestinal discomforts, such as diarrhea or constipation.* These side effects are usually mild and resolve on their own.

Is it suitable for Vegetarians?

Yes, our Berberine supplement is suitable for vegetarians.

Rated 4.7 out of 5 stars
Based on 122 reviews
Total 5 star reviews: 90 Total 4 star reviews: 32 Total 3 star reviews: 0 Total 2 star reviews: 0 Total 1 star reviews: 0
100%would recommend this product
122 reviews
  • T
    I recommend this product
    Rated 5 out of 5 stars
    2 months ago
    Good source

    Trust this company every supplement I've gotten has been accurately promoted

  • R
    I recommend this product
    Rated 4 out of 5 stars
    2 months ago
    Great for me

    Top-notch supplement I've tried.

  • D
    I recommend this product
    Rated 5 out of 5 stars
    2 months ago
    Great, I'm impressed.

    I am extremely pleased with its effects.

  • DM
    Destiny M.
    I recommend this product
    Rated 5 out of 5 stars
    2 months ago
    Added To My Healthy Living Lifestyle

    I Love This Product

  • W
    I recommend this product
    Rated 5 out of 5 stars
    2 months ago
    Feel the difference now

    Much less bloating and gas. Will keep on taking it

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