Zinc Quercetin with Epicor®

“Discover the Immune Wellness Blend with the Goodness of Fermentate”

Key Product Features and Benefits

• Supports Immune Function.*

• High-Metabolite Immunogens.*

• Supports Neutralize Free Radicals and Ease Oxidative Stress.*

• Supports GUT Microbiome & Digestive Health.*

• Supports Circulatory Health.*

• Formulated Using Clinically Studied Yeast Fermentate (EpiCor^®).*

• Suitable for Vegetarians.

Healthy Immune-Healthy You*

The body’s natural immune system, as the barrier, fights against foreign microbial invaders to lead a healthy life. An inactive lifestyle, poor nutrition, and unhygienic practices may impact the natural defense mechanism and affect your overall wellness. Sandhu’s research-based quality composition will support you in your wellness routine.* ^(1-16)

A Perfect Combo for Well-being*^(1-16)

Zinc supports many cellular functions and numerous enzymes that aid metabolism, digestion, nerve function, and much more.*^(1-4,8) For zinc to work effectively, it has to be pushed into the cells which would require a vehicle called ionophore.

Quercetin is a plant flavonoid, that acts as a vehicle (zinc ionophore) to transport zinc across the cell membrane, and deep into the cells, for better effect than zinc alone.* ⁽¹⁷⁾

EpiCor^® postbiotic is a dried yeast fermentate from Saccharomyces cerevisiae, which contains phospholipids, unsaturated fatty acids, antioxidants, polyphenols, phytosterols, beta-glucans, mannan, oligosaccharides, amino acids, vitamins, minerals, and other nutrients.* ^(5-7,11)

Transparency in Science

Immune Health*^(1-7)

Quercetin, a potent natural antioxidant, along with zinc, supports natural immune function by neutralizing free radicals and ease oxidative stress.*^(1,4,8-10) EpiCor^®, a clinically proven ingredient to support the body’s immune system.*^(5-7)

High-Metabolite Immunogens*^(5-7)

Formulated using EpiCor^®, a clinically proven mucosal immune supporter which supports antibody production, and helps modulate the body’s natural immune response year-round.*^(5-7)

Digestive & Circulatory Health*^(11,12-15)

EpiCor® is one of the most clinically researched postbiotics shown to positively support the gut microbiota.*⁽¹¹⁾ The anti-oxidative properties of quercetin have a supportive effect on circulatory health*^(12-15)

Why Do I Need Sandhu’s Zinc Quercetin with EPICOR^®?

• A research-based unique blend.

• At Sandhu’s, we use high-quality ‘Sophora japonica’flower bud-derived quercetin.*

• Formulated using EpiCor^®, a clinically studied & patented postbiotic.*^(5-7,11)

• Blended with zinc mono methionine, a highly absorbable form of zinc made by chelating zinc and amino acid methionine.*⁽¹⁸⁾

• Easy-to-Swallow Vegetable Capsules.

• Gluten, soy, dairy free & third-party tested.

• Formulated according to current Good Manufacturing Practices (cGMP).

• Formulated, tested, and packed in the USA.

References:

1. Prasad AS, Beck FW, Bao B, Fitzgerald JT, Snell DC, Steinberg JD, Cardozo LJ. Zinc supplementation decreases incidence of infections in the elderly: effect of zinc on generation of cytokines and oxidative stress. The American journal of clinical nutrition. 2007 Mar 1;85(3):837-44.
2. Mariani E, Neri S, Cattini L, Mocchegiani E, Malavolta M, Dedoussis GV, Kanoni S, Rink L, Jajte J, Facchini A. Effect of zinc supplementation on plasma IL-6 and MCP-1 production and NK cell function in healthy elderly: interactive influence of+ 647 MT1a and− 174 IL-6 polymorphic alleles. Experimental gerontology. 2008 May 1;43(5):462-71.
3. Fortes C, Forastiere F, Agabiti N, Fano V, Pacifici R, Virgili F, Piras G, Guidi L, Bartoloni C, Tricerri A, Zuccaro P. The effect of zinc and vitamin A supplementation on immune response in an older population. Journal of the American Geriatrics Society. 1998 Jan;46(1):19-26.
4. Bao B, Prasad AS, Beck FW, Fitzgerald JT, Snell D, Bao GW, Singh T, Cardozo LJ. Zinc decreases C-reactive protein, lipid peroxidation, and inflammatory cytokines in elderly subjects: a potential implication of zinc as an atheroprotective agent. The American journal of clinical nutrition. 2010 Jun 1;91(6):1634-41.
5. Jensen GS, Patterson KM, Barnes J, Schauss AG, Beaman R, Reeves SG, Robinson LE. A double-blind placebo-controlled, randomized pilot study: consumption of a high-metabolite immunogen from yeast culture has beneficial effects on erythrocyte health and mucosal immune protection in healthy subjects. The Open Nutrition Journal. 2008 Jul 25;2(1).
6. Schauss AG, Vojdani A. Discovery of edible fermentation product with unusual immune enhancing properties in humans.
7. Moyad MA, Robinson LE, Kittelsrud JM, Reeves SG, Weaver SE, Guzman AI, Bubak ME. Immunogenic yeast-based fermentation product reduces allergic rhinitis-induced nasal congestion: a randomized, double-blind, placebo-controlled trial. Advances in therapy. 2009 Aug;26:795-804.
8. Mariani E, Mangialasche F, Feliziani FT, Cecchetti R, Malavolta M, Bastiani P, Baglioni M, Dedoussis G, Fulop T, Herbein G, Jajte J. Effects of zinc supplementation on antioxidant enzyme activities in healthy old subjects. Experimental gerontology. 2008 May 1;43(5):445-51.
9. Askari G, Ghiasvand R, Feizi A, Ghanadian SM, Karimian J. The effect of quercetin supplementation on selected markers of inflammation and oxidative stress. Journal of research in medical sciences: the official journal of Isfahan University of Medical Sciences. 2012 Jul;17(7):637.
10. Tsao JP, Bernard JR, Hsu HC, Hsu CL, Liao SF, Cheng I. Short-Term Oral Quercetin Supplementation Improves Post-exercise Insulin Sensitivity, Antioxidant Capacity and Enhances Subsequent Cycling Time to Exhaustion in Healthy Adults: A Pilot Study. Frontiers in Nutrition. 2022:872.
11. Pinheiro I, Robinson L, Verhelst A, Marzorati M, Winkens B, den Abbeele PV, Possemiers S. A yeast fermentate improves gastrointestinal discomfort and constipation by modulation of the gut microbiome: results from a randomized double-blind placebo-controlled pilot trial. BMC complementary and alternative medicine. 2017 Dec;17:1-20.
12. Lee KH, Park E, Lee HJ, Kim MO, Cha YJ, Kim JM, Lee H, Shin MJ. Effects of daily quercetin-rich supplementation on cardiometabolic risks in male smokers. Nutrition research and practice. 2011 Feb 1;5(1):28-33.
13. Hubbard GP, Wolffram S, Lovegrove JA, Gibbins JM. Ingestion of quercetin inhibits platelet aggregation and essential components of the collagen‐stimulated platelet activation pathway in humans. Journal of Thrombosis and Haemostasis. 2004 Dec 1;2(12):2138-45.
14. Edwards RL, Lyon T, Litwin SE, Rabovsky A, Symons JD, Jalili T. Quercetin reduces blood pressure in hypertensive subjects. The Journal of nutrition. 2007 Nov 1;137(11):2405-11.
15. Egert, S., Bosy-Westphal, A., Seiberl, J., Kürbitz, C., Settler, U., Plachta-Danielzik, S., Wagner, A.E., Frank, J., Schrezenmeir, J., Rimbach, G. and Wolffram, S., 2009. Quercetin reduces systolic blood pressure and plasma oxidised low-density lipoprotein concentrations in overweight subjects with a high-cardiovascular disease risk phenotype: a double-blinded, placebo-controlled cross-over study. British journal of nutrition, 102(7), pp.1065-1074.
16. Duarte J, Pérez‐Palencia R, Vargas F, Angeles Ocete M, Pérez‐Vizcaino F, Zarzuelo A, Tamargo J. Antihypertensive effects of the flavonoid quercetin in spontaneously hypertensive rats. British journal of pharmacology. 2001 May;133(1):117-24.
17. Dabbagh-Bazarbachi H, Clergeaud G, Quesada IM, Ortiz M, O’Sullivan CK, Fernández-Larrea JB. Zinc ionophore activity of quercetin and epigallocatechin-gallate: from Hepa 1-6 cells to a liposome model. Journal of Agricultural and Food Chemistry. 2014 Aug 13;62(32):8085-93.
18. Rosado JL, Muñoz E, López P, Allen LH. Absorption of zinc sulfate, methionine, and polyascorbate in the presence and absence of a plant-based rural Mexican diet. Nutrition Research. 1993 Oct 1;13(10):1141-51.

Zinc (as Zinc Mono Methionine Chelate Complex), Quercetin (as Quercetin Dihydrate) Japanese Sophora (Sophora Japonica) (Flower Buds) Extract, EpiCor® (Dried Yeast Fermentate) (from Saccharomyces Cerevisiae).

Other Ingredients: Vegetable Cellulose Capsules, Microcrystalline Cellulose, Magnesium Stearate, and Silicon Dioxide.

Take 2 capsules daily with food or as directed by your healthcare professional.

Caution: Consult your healthcare provider prior to the use of this supplement, if you are pregnant or nursing, taking medications, or have a medical condition. Discontinue use and consult your doctor if any adverse reactions occur. Keep out of the reach of children. Do not use if the safety seal is damaged or missing. Store in a cool and dry place. Yellowish color and granularity may occur due to seasonal harvest and process of Quercetin. Speckle variation is due to EpiCor® as a dried yeast fermentate.