GUT HEALTH

Discover the complete blend of Prebiotic, Probiotic, Postbiotic, and Preservation support for complete GUT Care.*

Key Benefits and Product Features:

• Supports Gut Microflora Balance.*

• Supports Healthy Gut Lining.*

• Supports Regularity.*

• Supports Healthy Weight Management.*

• Supports Healthy Mood.*

• Supports Positive Energy Level.*

• Supports Healthy Immune Function.*

• Delayed-Release Capsule Technology.

• No Refrigeration is Needed.

Why GUT Health?

The gut is home to various species of friendly bacteria that collectively form the “Gut microbiome” which is the foundation for a healthy gut and physiological condition. This microbiome balance can directly influence our immune system, circulatory health, brain health, sleep, mood, digestion, and overall wellness. Busy lifestyle, stress, improper sleep, unhealthy and inactive lifestyle are unavoidable parts of modern life that may disrupt the gut microbiome balance.

Sandhu’s high-quality research-based formulation with clinically evaluated prebiotic, probiotic, and postbiotic with preservation support in a delayed-release capsule to prevent nutrients from being broken down in the stomach so they could be released in the small intestine where it can thrive.*⁽²¹⁾ This complete formula may help in reaching your wellness goal.*

“4P’s for Proper GUT”

Transparency in Science

SunFiber^® (Prebiotic)

SunFiber® (partially hydrolyzed guar gum), is a 100% water-soluble, clinically studied prebiotic fiber, unique in comparison to other non-galactomannan-based fibers.*^{(1-3,11,14,15,19)} It feeds beneficial gut bacteria, and the fermentation results in high levels of short-chain fatty acids (SCFA), which supports the colon and are beneficial to intestinal health.*^{(1-3,11,14,15,17)}

LactoSpore^® (Probiotic)

LactoSpore® (2 Billion CFUs, Bacillus Coagulans, MTCC 5856) is a clinically evaluated, shelf-stable probiotics.*⁽⁴⁾ It produces lactic acid, which supports regulating the bad bacteria and helps colonize the good bacteria to maintain a healthy gut and helps balance intestinal flora.*^{(4,5,13,16,17)}

CoreBiome^® (Postbiotic)

CoreBiome^® (Standardized to contain 30% Tributyrin), reaches both the small and large intestines to support the integrity of the gut lining to help ensure your gut is in the best condition.*^(8-10,18,21)

Fermented L –Glutamine (KQ^®) (Preservation Support)

L –Glutamine (KQ^®) is a science-based conditional amino acid that helps on tight junctions and supports maintaining healthy gut lining.*^(7,12,20)

DRcaps^®(Delayed-Release Capsules)

To prevent nutrients from being broken down in the stomach so they could be released in the small intestine.*⁽²²⁾

Why Sandhu’s GUT Health?

• Science-Based Composition.

• Unique Blend contains Clinically Tested Prebiotics, Probiotic, and Postbiotic with Time-tested Preservation Support.*

• Delayed Release Capsule Technology.

• Quality Proven Ingredients.

• No Refrigeration is Needed.

• Gluten, Soy, Dairy-Free, and Third-Party Tested.

• Formulated According to current Good Manufacturing Practice (cGMP).

References:

1. Yasukawa Z, Inoue R, Ozeki M, Okubo T, Takagi T, Honda A, Naito Y. Effect of repeated consumption of partially hydrolyzed guar gum on fecal characteristics and gut microbiota: a randomized, double-blind, placebo-controlled, and parallel-group clinical trial. Nutrients. 2019 Sep 10;11(9):2170.
2. Rosli D, Shahar S, Manaf ZA, Lau HJ, Yusof NY, Haron MR, Majid HA. Randomized controlled trial on the effect of partially hydrolyzed guar gum supplementation on diarrhea frequency and gut microbiome count among pelvic radiation patients. Journal of Parenteral and
3. Kapoor MP, Koido M, Kawaguchi M, Timm D, Ozeki M, Yamada M, Mitsuya T, Okubo T. Lifestyle related changes with partially hydrolyzed guar gum dietary fiber in healthy athlete individuals–A randomized, double-blind, crossover, placebo-controlled gut microbiome clinical study. Journal of Functional Foods. 2020 Sep 1;72:104067.
4. Majeed M, Nagabhushanam K, Natarajan S, Sivakumar A, Pande A, Majeed S, Ali F. A double-blind, placebo-controlled, parallel study evaluating the safety of Bacillus coagulans MTCC 5856 in healthy individuals. J Clin Toxicol. 2016;6(283):2161-0495.
5. Minamida K, Nishimura M, Miwa K, Nishihira J. Effects of dietary fiber with Bacillus coagulans lilac-01 on bowel movement and fecal properties of healthy volunteers with a tendency for constipation. Bioscience, Biotechnology, and Biochemistry. 2015 Feb 1;79(2):300-6.
6. Majeed MU, Natarajan S, Sivakumar A, Ali F, Pande AN, Majeed S, Karri SK. Evaluation of anti-diarrhoeal activity of Bacillus coagulans MTCC 5856 and its effect on gastrointestinal motility in Wistar rats. International Journal of Pharma and Bio Sciences. 2016;7(1):P311â.
7. Zhou Q, Verne ML, Fields JZ, Lefante JJ, Basra S, Salameh H, Verne GN. Randomised placebo-controlled trial of dietary glutamine supplements for postinfectious irritable bowel syndrome. Gut. 2019 Jun 1;68(6):996-1002.
8. Cresci GA, Glueck B, McMullen MR, Xin W, Allende D, Nagy LE. Prophylactic tributyrin treatment mitigates chronic‐binge ethanol‐induced intestinal barrier and liver injury. Journal of Gastroenterology and Hepatology. 2017 Sep;32(9):1587-97.
9. Glueck B, Han Y, Cresci GA. Tributyrin supplementation protects immune responses and vasculature and reduces oxidative stress in the proximal colon of mice exposed to chronic-binge ethanol feeding. Journal of Immunology Research. 2018 Oct;2018.
10. Miragoli F, Patrone V, Prandini A, Sigolo S, Dell’Anno M, Rossi L, Senizza A, Morelli L, Callegari ML. Implications of tributyrin on gut microbiota shifts related to performances of weaning piglets. Microorganisms. 2021 Mar 12;9(3):584.
11. Inoue R, Sakaue Y, Kawada Y, Tamaki R, Yasukawa Z, Ozeki M, Ueba S, Sawai C, Nonomura K, Tsukahara T, Naito Y. Dietary supplementation with partially hydrolyzed guar gum helps improve constipation and gut dysbiosis symptoms and behavioral irritability in children with autism spectrum disorder. Journal of clinical biochemistry and nutrition. 2019;64(3):217-23.
12. Rastgoo S, Ebrahimi-Daryani N, Agah S, Karimi S, Taher M, Rashidkhani B, Hejazi E, Mohseni F, Ahmadzadeh M, Sadeghi A, Hekmatdoost A. Glutamine supplementation enhances the effects of a low FODMAP diet in irritable bowel syndrome management. Frontiers in Nutrition. 2021:1079.
13. Balliett M, Burke JR. Changes in anthropometric measurements, body composition, blood pressure, lipid profile, and testosterone in patients participating in a low-energy dietary intervention. Journal of chiropractic medicine. 2013 Mar 1;12(1):3-14.
14. Van de Ven ML, Westerterp-Plantenga MS, Wouters L, Saris WH. Effects of liquid preloads with different fructose/fibre concentrations of subsequent food intake and ratings of hunger in women. Appetite. 1994 Oct 1;23(2):139-46.
15. Lluch A, Hanet-Geisen N, Salah S, Salas-Salvadó J, L’Heureux-Bouron D, Halford JC. Short-term appetite-reducing effects of a low-fat dairy product enriched with protein and fibre. Food quality and preference. 2010 Jun 1;21(4):402-9.
16. Balliett M, Burke JR. Changes in anthropometric measurements, body composition, blood pressure, lipid profile, and testosterone in patients participating in a low-energy dietary intervention. Journal of chiropractic medicine. 2013 Mar 1;12(1):3-14.
17. Majeed M, Nagabhushanam K, Arumugam S, Majeed S, Ali F. Bacillus coagulans MTCC 5856 for the management of major depression with irritable bowel syndrome: a randomised, double-blind, placebo controlled, multi-centre, pilot clinical study. Food & nutrition research. 2018;62.
18. Grosicki GJ, Riemann BL, Flatt AA, Valentino T, Lustgarten MS. Self-reported sleep quality is associated with gut microbiome composition in young, healthy individuals: a pilot study. Sleep medicine. 2020 Sep 1;73:76-81.
19. Sakai S, Kamada Y, Takano H, Ichikawa M, Kurimoto M, Katsuyama HK, Nishihira J, Sasaki M. Continuous partially hydrolyzed guar gum intake reduces cold-like symptoms: a randomized, placebo-controlled, double-blinded trial in healthy adults. European Review for Medical and Pharmacological Sciences. 2022 Jan 1;26(14):5154-63.
20. Cengiz M, Uysal BB, Ikitimur H, Ozcan E, Islamoğlu MS, Aktepe E, Yavuzer H, Yavuzer S. Effect of oral l-Glutamine supplementation on Covid-19 treatment. Clinical nutrition experimental. 2020 Oct 1;33:24-31.
21. Shinde T, Vemuri R, Shastri MD, Perera AP, Tristram S, Stanley R, Eri R. Probiotic Bacillus coagulans MTCC 5856 spores exhibit excellent in-vitro functional efficacy in simulated gastric survival, mucosal adhesion and immunomodulation. Journal of Functional Foods. 2019 Jan 1;52:100-8.
22. Amo R. DRcaps® capsules achieve delayed release properties for nutritional ingredients in human clinical study. No. BAS. 2014;420.

SunFiber® Guar Fiber (Organic), LactoSpore® (Bacillus coagulans MTCC 5856) (2 Billion CFUs), CoreBiome® (Standardized to 30% Tributyrin) and L-Glutamine (Fermented) (KQ®).

Other Ingredients: Drcaps® Delayed Release Vegetable Capsules (Hypromellose, Water, Gellan Gum), Silicon Dioxide, MCT Powder.

Take 4 capsules a day with food or as directed by your health care professional.

Caution: Consult your health care provider prior to the use of this supplement, if you are pregnant or nursing, taking medication, or have a medical condition. Discontinue use and consult your doctor in any adverse reactions occur. Keep out of the reach of children. Do not use if safety seal is damaged or missing. Store in a cool and dry place.