Sleep and Magnesium Glycinate

Sleep and Magnesium Glycinate

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Sleep and Magnesium Glycinate

Sleep and Magnesium Glycinate

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Supports Relaxation and Sleep.* Supports Brain & Immune Health.* Supports Bone, Muscle, & Nerve Health*

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Highlights

Sleep:
Science-Based Unique Formulation.
Contains Quality Amino Acids and Mineral.*
High Absorbable form of Magnesium (as Magnesium Citrate).*
Easy-to-Swallow Capsules.

Magnesium Glycinate:
High Absorbable Forms of Magnesium to Support Muscle and Nerve Health.*
Provides 50% of Your Daily Magnesium Requirement that Helps Healthy Metabolism.*
100% Chelated Magnesium Glycinate to Support Relaxation and Restful Sleep*
No Laxative Effect, Gentle on Your Stomach.*

Suggested Usage

Sleep:
Take 2 capsules 30 minutes before bedtime or as directed by your health care professional.

Magnesium Glycinate:
Take one capsule a day, preferably with food or as directed by your health care professionals.

Ingredients

Sleep:
Magnesium (as Magnesium Citrate), GABA (Gamma-Aminobutyric Acid), L-Theanine, 5-HTP (L-5-Hydroxytryptophan), and Melatonin.
Other ingredients: Vegetable Cellulose Capsules, Microcrystalline Cellulose, Magnesium Stearate.

Magnesium Glycinate:
Magnesium Glycinate Chelate
Other Ingredients:   Rice Hull Extract , Vegetable Cellulose Capsule

prod-sleepezz-melatonin6mg

Why Sandhu’s Sleep + Magnesium Glycinate?

Rest easy, wake refreshed

Restful sleep and optimal mineral balance are essential for overall well-being. While we sleep, our bodies undergo repair and rejuvenation, and our brains sift
through and organize the information gathered throughout the day.

Modern lifestyles, diet, and stress make quality sleep a challenge for many people
today.

To help achieve Quality sleep and balanced minerals at Sandhu’s, we offer an effective bundle Sleep + Magnesium Glycinate making it an excellent choice for those pursuing an active, vibrant lifestyle.

How Does this Combo Work?

Supports You in Reaching Your Wellness Goals!

Sleep helps calm the brain, supports relaxation and helps regulate sleep cycles. It also aids in maintaining a positive mood.* (1-3)
Magnesium Glycinate Magnesium helps convert carbohydrates and fats into energy, supports muscle function, and aids in the absorption of calcium and other key minerals for strong bones.* It also encourages relaxation and supports melatonin production to regulate sleep-wake cycles.*(20-31)
This combination provides a powerful synergy for relaxation and restful sleep, along with benefits for brain and immune health and the maintenance of strong bones.*

Sleep

Healthy Sleep, Healthy You
Sleep is an essential part of our daily routine and plays a critical role in our overall health and well-being. During sleep, our body repairs and rejuvenates itself, and our brain processes the information we have accumulated throughout the day. Modern population struggles to get enough quality sleep because of various lifestyles, diet, and stress. If you're struggling with sleep-related challenges, it's important to take action to improve the quality and quantity of your sleep. Enjoying restful quality sleep with a healthy sleep-wake pattern may be  simple when you consider adding Sandhu’s safe sleep supplement.*

Transparency in Science
Why Gamma-Aminobutyric Acid (GABA)?
GABA is a naturally occurring amino acid that supports brain cell communication to regulate the body's metabolic actions which are essential for quality sleep and relaxation.*(1-3)
Why L-Theanine?
It is an amino acid, chemically similar to GABA, that supports calmness by controlling noises in your brain and helps to keep you clear and focused without a groggy feeling upon waking up.*(6,7,13)

Why Melatonin?
Melatonin is a non-habitant and sleep-friendly hormone that supports setting the natural alarm in your sleep-wake clock.* (5,8,9,19) It also supports maintaining a healthy brain.*(18)

Why 5-hydroxytryptophan (5-HTP)?
5-HTP acts as a serotonin precursor, which supports staying in a positive mood and getting into a cyclic sleep by regulating the happy hormone serotonin.*(4,11,12)

Why Magnesium?
Magnesium is an essential mineral that supports the transition to deep sleep by helping muscle and overall relaxation.*(10,14-18)

Magnesium Glycinate

Why Sandhu’s Magnesium Glycinate?
Many types of magnesium supplements are available on the market. But they are not well absorbed by your digestive system.
Sandhu’s Magnesium glycinate is formed by combining elemental magnesium with the amino acid glycine. This form of magnesium is highly bioavailable, meaning the magnesium is easily absorbed through your small intestine.*

Benefits of High Absorbable Sandhu’s Magnesium Glycinate
Magnesium, an essential mineral, plays a crucial role in maintaining overall well-being by influencing various bodily processes. It catalyzes over 300 biochemical reactions, making it indispensable for the body's proper functioning.

Helps Enhance Energy Production*
Magnesium serves as a cofactor for various enzymes involved in carbohydrate and fat metabolism.* These enzymes are responsible for converting these macronutrients into energy-yielding molecules, such as adenosine triphosphate (ATP), the primary energy currency of cells.* By optimizing these metabolic processes, magnesium supports a steady supply of energy to power daily activities and helps combat tiredness.*(20-23)

Supports Healthy Muscle and Nerve Function*
Magnesium supports healthy muscle functioning that helps in smooth and coordinated movements.* Additionally, magnesium supports the transmission of nerve impulses, enabling effective communication between the brain and various parts of the body.* This supports optimal muscle control, coordination, and sensory perception.*(24-26)

Helps Maintain the Bones Healthy.*
Magnesium plays a pivotal role in bone health by supporting the absorption and utilization of essential nutrients, including calcium, vitamin D, copper, and zinc.* These nutrients work together to maintain bone density, structure, and strength.*(27-30)

Helps Ease Occasional Stress*
During periods of stress, the body releases stress hormones, such as cortisol, which can lead to muscle tension and anxiety. Magnesium helps combat these effects by supporting muscle relaxation and minimizing nerve excitability.*(24)

Supports Calmness and Relaxation*
It plays a role in regulating the production of neurotransmitters like GABA (gamma-aminobutyric acid), which is responsible for inducing relaxation and reducing anxiety.* Magnesium helps enhance GABA activity which supports a sense of calm and mental wellness.*(29,30)

Supports Restful Sleep*
Magnesium plays a crucial role in regulating melatonin production, a hormone that signals the body to prepare for sleep.* By optimizing melatonin levels, magnesium helps establish a regular sleep-wake cycle, supporting faster sleep onset and deeper, more restful sleep.*(29-31)

1. Shin YY, Byun JI, Chung SE, Seong MJ, Cho HA, Cha HK, Shin WC. Effect of low and high-dose GABA from unpolished rice-germ on timing and quality of sleep: a randomized double-blind placebo-controlled trial. Journal of Sleep Medicine. 2016 Dec 30;13(2):60-6.​

2. Hinton T, Jelinek HF, Viengkhou V, Johnston GA, Matthews S. Effect of GABA-fortified oolong tea on reducing stress in a university student cohort. Frontiers in Nutrition. 2019 Mar 26;6:27.​

3. Abdou AM, Higashiguchi S, Horie K, Kim M, Hatta H, Yokogoshi H. Relaxation and immunity enhancement effects of γ‐aminobutyric acid (GABA) administration in humans. Biofactors. 2006;26(3):201-8.​

4. Meloni M, Figorilli M, Carta M, Tamburrino L, Cannas A, Sanna F, Defazio G, Puligheddu M. Preliminary finding of a randomized, double-blind, placebo-controlled, crossover study to evaluate the safety and efficacy of 5-hydroxytryptophan on REM sleep behavior disorder in Parkinson’s disease. Sleep and Breathing. 2022 Sep;26(3):1023-31.​

5. Gooneratne NS, Edwards AY, Zhou C, Cuellar N, Grandner MA, Barrett JS. Melatonin pharmacokinetics following two different oral surge‐sustained release doses in older adults. Journal of pineal research. 2012 May;52(4):437-45.​

6. Evans M, McDonald AC, Xiong L, Crowley DC, Guthrie N. A randomized, triple-blind, placebo-controlled, crossover study to investigate the efficacy of a single dose of AlphaWave® l-theanine on stress in a healthy adult population. Neurology and Therapy. 2021 Dec;10:1061-78.​

7. Hidese S, Ota M, Wakabayashi C, Noda T, Ozawa H, Okubo T, Kunugi H. Effects of chronic l-theanine administration in patients with major depressive disorder: an open-label study. Acta neuropsychiatrica. 2017 Apr;29(2):72-9.​

8. Lockley SW, Skene DJ, James K, Thapan K, Wright J, Arendt J. Melatonin administration can entrain the free-running circadian system of blind subjects. J Endocrinol. 2000 Jan 1;164(1):R1-6.​

9. Sack RL, Brandes RW, Kendall AR, Lewy AJ. Entrainment of free-running circadian rhythms by melatonin in blind people. New England Journal of Medicine. 2000 Oct 12;343(15):1070-7.​

10. Abbasi B, Kimiagar M, Sadeghniiat K, Shirazi MM, Hedayati M, Rashidkhani B. The effect of magnesium supplementation on primary insomnia in elderly: A double-blind placebo-controlled clinical trial. Journal of research in medical sciences: the official journal of Isfahan University of Medical Sciences. 2012 Dec;17(12):1161.​

11. Sutanto C, Heng CW, Gan AX, Wang X, Fam J, Kim JE. The impact of 5-Hydroxytryptophan supplementation on sleep quality of older adults in Singapore: A randomized controlled trial. Current Developments in Nutrition. 2021 Jun;5(2):372.​

12. Meloni M, Figorilli M, Carta M, Tamburrino L, Cannas A, Sanna F, Defazio G, Puligheddu M. Preliminary finding of a randomized, double-blind, placebo-controlled, crossover study to evaluate the safety and efficacy of 5-hydroxytryptophan on REM sleep behavior disorder in Parkinson’s disease. Sleep and Breathing. 2022 Sep;26(3):1023-31.​

13. Hidese S, Ogawa S, Ota M, Ishida I, Yasukawa Z, Ozeki M, Kunugi H. Effects of L-theanine administration on stress-related symptoms and cognitive functions in healthy adults: a randomized controlled trial. Nutrients. 2019 Oct 3;11(10):2362.​

14. Cao Y, Zhen S, Taylor AW, Appleton S, Atlantis E, Shi Z. Magnesium intake and sleep disorder symptoms: findings from the Jiangsu Nutrition Study of Chinese adults at five-year follow-up. Nutrients. 2018 Sep 21;10(10):1354.​

15. Tarleton EK, Littenberg B, MacLean CD, Kennedy AG, Daley C. Role of magnesium supplementation in the treatment of depression: A randomized clinical trial. PloS one. 2017 Jun 27;12(6):e0180067.​

16. Reno AM, Green M, Killen LG, O'Neal EK, Pritchett K, Hanson Z. Effects of Magnesium Supplementation on Muscle Soreness and Performance. Journal of Strength and Conditioning Research. 2022 Aug 1;36(8):2198-203.​

17. Spivey WH, Skobeloff EM, Levin RM: Effect of magnesium chloride on rabbit bronchial smooth muscle. Ann Emerg Med 1990; 19:1107–12.​

18. Hirota K, Sato T, Hashimoto Y, Yoshioka H, Ohtomo N, Ishihara H, Matsuki A: Relaxant effect of magnesium and zinc on histamine-induced bronchoconstriction in dogs. Crit Care Med 1999; 27:1159–63.​

19. Asayama K, Yamadera H, Ito T, Suzuki H, Kudo Y, Endo S. Double blind study of melatonin effects on the sleep-wake rhythm, cognitive and non-cognitive functions in Alzheimer type dementia. Journal of Nippon Medical School. 2003;70(4):334-41. ​

20. Guerrero‐Romero F, Rodríguez‐Morán M. Magnesium improves the beta‐cell function to compensate variation of insulin sensitivity: double‐blind, randomized clinical trial. European journal of clinical investigation. 2011 Apr;41(4):405-10.

21. ELDerawi WA, Naser IA, Taleb MH, Abutair AS. The effects of oral magnesium supplementation on glycemic response among type 2 diabetes patients. Nutrients. 2018 Dec 26;11(1):44.

22. Reno AM, Green M, Killen LG, O'Neal EK, Pritchett K, Hanson Z. Effects of Magnesium Supplementation on Muscle Soreness and Performance. Journal of Strength and Conditioning Research. 2022 Aug 1;36(8):2198-203.

23. Córdova A, Mielgo-Ayuso J, Roche E, Caballero-García A, Fernandez-Lázaro D. Impact of magnesium supplementation in muscle damage of professional cyclists competing in a stage race. Nutrients. 2019 Aug 16;11(8):1927.

24. Macian N, Dualé C, Voute M, Leray V, Courrent M, Bodé P, Giron F, Sonneville S, Bernard L, Joanny F, Menard K. Short-term magnesium therapy alleviates moderate stress in patients with fibromyalgia: A randomized double-blind clinical trial. Nutrients. 2022 May 17;14(10):2088.

25. Starobrat-Hermelin B, Kozielec T. The effects of magnesium physiological supplementation on hyperactivity in children with attention deficit hyperactivity disorder (ADHD). Positive response to magnesium oral loading test. Magnesium research. 1997 Jun 1;10(2):149-56

26. Ryder KM, Shorr RI, Bush AJ, Kritchevsky SB, Harris T, Stone K, Cauley J, Tylavsky FA. Magnesium intake from food and supplements is associated with bone mineral density in healthy older white subjects. Journal of the American Geriatrics Society. 2005 Nov;53(11):1875-80.

27. Dimai HP, Porta S, Wirnsberger G, Lindschinger M, Pamperl I, Dobnig H, Wilders-Truschnig M, Lau KH. Daily oral magnesium supplementation suppresses bone turnover in young adult males. The Journal of Clinical Endocrinology & Metabolism. 1998 Aug 1;83(8):2742-8.

28. Carpenter TO, DeLucia MC, Zhang JH, Bejnerowicz G, Tartamella L, Dziura J, Petersen KF, Befroy D, Cohen D. A randomized controlled study of effects of dietary magnesium oxide supplementation on bone mineral content in healthy girls. The Journal of Clinical Endocrinology & Metabolism. 2006 Dec 1;91(12):4866-72.

29. Matias CN, Santos DA, Monteiro CP, Vasco AM, Baptista F, Sardinha LB, Laires MJ, Silva AM. Magnesium intake mediates the association between bone mineral density and lean soft tissue in elite swimmers. Magnesium Research. 2012 Jul 1;25(3):120-5.

30. Held K, Antonijevic IA, Künzel H, Uhr M, Wetter TC, Golly IC, Steiger
A, Murck H. Oral Mg2+ supplementation reverses age-related neuroendocrine and sleep EEG changes in humans. Pharmacopsychiatry. 2002 Jul;35(04):135-43.

31. Nielsen FH, Johnson LK, Zeng H. Magnesium supplementation improves indicators of low magnesium status and inflammatory stress in adults older than 51 years with poor quality sleep.

32. Abbasi B, Kimiagar M, Sadeghniiat K, Shirazi MM, Hedayati M, Rashidkhani B. The effect of magnesium supplementation on primary insomnia in elderly: A double-blind
placebo-controlled clinical trial. Journal of research in medical sciences: the official journal of Isfahan University of Medical Sciences. 2012 Dec;17(12):1161.

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